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Results of a meta-analysis;


Multispecies probiotics 

benefit children with eczema

Over the past decades, the incidence of allergic diseases has markedly increased.   A recently published meta-analysis evaluated the effect of 13 randomized controlled trials on the effect of probiotics on the treatment of atopic dermatitis. Whereas some single strain probiotics did not show beneficial effect, the multispecies formulations did.

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Allergic rise

In Western societies, the prevalence of allergy is rising and becoming a major global public health issue.  Eczema, or atopic dermatitis (AD), is one of the most common allergic disorders among infants and children, affecting 10-20% of the population. The specific cause of eczema remains unknown, but it is believed to develop due to a combination of hereditary (genetic) and environmental factors. Given their ability to modulate the immune system, probiotics are becoming increasingly attractive as a treatment option for allergies.

A recently published meta-analysis aimed to assess the effects of probiotics on eczema in children. The researchers analysed the outcomes of 13 studies, including two studies of Winclove: the Niers trial with Ecologic® Panda (2009) and the Yesilova triall with Ecologic® AllergyCare (2012).



All diseases begin in the gut 


On the articulations. The genuine works of Hippocrates (2002)

Research results

Significantly higher SCORAD (Scoring Atopic Dermatitis) were observed among controls compared to the probiotic groups.The researchers also performed subgroup analyses on single strains and multispecies formulations. They found that the single strains Lactobacillus rhamnosus and Lactobacillus plantatrum alone did not significantly lower SCORAD values in children with AD. However, the single strains, Lactobacillus fermentum and Lactobacillus salivarius and mixtures of probiotic strains did show significant effects on SCORAD values in children with AD.


Overall, the data suggested a benefit of probiotics supplementation in children with AD. Several other research groups have performed meta-analyses to evaluate the effectiveness of probiotics in AD. The findings are in line with other research that the evidence for probiotics as a useful treatment of AD in children is convincing.

It is believed that probiotic supplementation may promote a healthier gut microbiota profile, thereby boosting the immune response and preventing development of allergy/eczema.

Read the Niers trial 



Read the Yesilova trial 



Read the meta-analysis 








Multispecies probiotics and atopic dermatitis

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