Fatigue and abdominal complaints in chronic illnesses
MyOwnResearch focuses on the frequently seen combination of fatigue and abdominal symptoms in patients with chronic illnesses, for whom a treatment with probiotics and other supplements may be a potential solution. This is based on the premise that gut health is directly related to overall health as well as brain function. The treatment will differ from patient to patient and will be tailored to the state of an individual’s gut health. In addition, the patients themselves will decide what they want the treatment to achieve (e.g. feeling less tired, less pain, sleep better). This approach will allow the researchers to find subgroups and help figure out why certain treatments are effective in some, but not all, patients.
Practice based evidence building
MyOwnResearch is ‘practice based evidence building’, which is a new type of research that can help gain insight in diseases and chronic illnesses of which the underlying mechanisms are unclear, or for which we do not yet have an adequate treatment.
Is the Gold Standard still enough?
Scientific evidence rendered by randomized, double blind, placebo controlled studies is considered to be the best basis for medical treatment (the so called Gold Standard). This kind of approach gives us an estimate of the effectiveness of a treatment, based on an average patient. However, there are many poorly understood diseases, such as chronic fatigue syndrome, in which a large variety of factors play a role, and where only a relatively small part of the patients respond to traditional evidence based treatments.