The ability of Ecologic® SENSE to positively influence cognitive status has been established in several studies. For example, Ecologic® SENSE has been tested in collaboration with Leiden University on cognitive reactivity to sad mood, a vulnerability marker for depression. Compared to participants who received the placebo intervention, the Ecologic® SENSE group showed a significantly reduced overall cognitive reactivity to sad mood. The researchers concluded that the intake of this probiotic may help reduce negative thoughts associated with sad mood. These promising results led to a large follow up study that is currently running in an elderly population.
In collaboration with the University of Technology Sydney, Australia, the effect of Ecologic® SENSE on reducing depressive symptoms is planned. This randomized placebo- controlled trial will investigate whether administration of Ecologic® SENSE is effective in reducing levels of depression in a population of depressed adults. Participants will consume Ecologic® SENSE daily and provide measures of mood throughout the study period.
Another randomized, placebo-controlled trial in collaboration with Radboud University and Medical Centrum, The Netherlands, will investigate the impact of Ecologic® SENSE on neurocognitive measures of emotion & executive functioning in healthy females by measuring brain activity via fMRI scans.
The results of these studies will contribute to the accumulating evidence that the intestinal microbiota may also play a role in other CNS involved conditions.
Note: Ecologic® SENSE is a probiotic concept formulation for business to business purposes. The formulation is not commercially available.